HORIZON HEALTH ECONOMICS

We help life sciences teams navigate complex evidence, build credible economic models, and communicate value with clarity.

0Models built
0Publications
0Diseases modelled
0Countries

About

A consultancy built around delivery

Horizon Health Economics is a consultancy focused on health economic modelling and healthcare data analytics. We are a small, agile team of technical experts focused on delivering impact through health economics.

Technical excellence

Senior modellers and analysts with extensive experience across industry, consultancy, academia and payer settings.

Accountable

The experts that design your projects also deliver them, ensuring accountability, consistency, and quality at every stage.

Focused

We tailor our approach to each project’s unique challenges, opportunities and target audience.

Philosophy

Models that earn their keep

“All models are wrong, but some are useful.” — George E. P. Box
Pathway from evidence relationships to informed decisions

Every model simplifies the representation of reality, but the true value of each modelling application lies in how it helps us understand and inform real-world decisions.

We build models that reveal key relationships and value insights, that make the best use of available data, and that help clarify and quantify uncertainty. By focusing on practical insight over abstraction we help our clients act with confidence in complex evidence generation landscapes.

We design our models to communicate with maximum impact and clarity, ensuring deliverables are always tailored to the target audience.

Team

Experienced, collaborative, and accountable

A close-knit team with long-standing professional relationships and an established track record of working together to deliver clear, credible and high-quality health economics and outcomes research.

Portrait of Tom Ward

Tom Ward

Director

A seasoned modeller and analyst with 14 years experience across consultancy, academia and industry settings, with a personal interest in application development.

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Tom Ward

Director

LinkedIn profile

Tom has a background in pure mathematics, and is a seasoned health economist with 14 years of experience across consultancy and industry roles. His primary focus has been the development of global health economic models that have driven HTA approvals, shaped peer-reviewed publications, and leveraged statistical analysis of clinical trials and real-world evidence studies.

He has a particular interest in R Shiny application development and the ongoing evolution of early economic modelling approaches in industry, and has worked across a diverse range of therapy areas, with a recent focus on oncology, respiratory, chronic kidney disease, and liver disease indications.

  • Decision modelling
  • Excel
  • VBA
  • R
  • Shiny
  • HTA
  • Python
  • Oncology
  • Respiratory
  • CKD
  • Liver disease
Portrait of Oli Darlington

Oli Darlington

Director

A health economist specialising in modelling, evidence synthesis, ITCs, and HTA strategy, with experience in consulting, and public health roles.

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Oli Darlington

Director

LinkedIn profile

Oli is a health economist with a decade of experience specialising in model conceptualization and development, evidence synthesis including indirect comparisons and meta-analysis, and HTA strategy. He has led diverse technical teams including health economists, statisticians and systematic reviewers to deliver complex evidence synthesis projects for both HTA submission and peer-reviewed publication.

He has extensive hands-on delivery experience across public and private sectors, including leading external review groups for global HTA agencies. Oli has developed economic models and conducted evidence synthesis projects across a broad range of therapy areas, including cardiovascular disease (coronary artery disease, heart failure, hyperlipidemia), CKD, oncology, respiratory, infectious and rare diseases.

  • Decision modelling
  • Excel
  • VBA
  • R
  • Shiny
  • EAG
  • HTA
  • ITC
  • Public health
  • Cardio-renal
  • Infectious diseases
  • Oncology
  • Respiratory
  • Rare diseases
Portrait of Alex van Doornewaard

Alex van Doornewaard

Principal Scientist

A health economist with a decade of experience delivering and leading decision modelling, evidence review, and ITC projects for pharmaceutical, diagnostic, and policy interventions across European markets.

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Alex van Doornewaard

Principal Scientist

LinkedIn profile

Alex is a trained health economist with 10 years of experience in the consultancy space. Focused on decision modelling, his research expertise encompasses evidence review and synthesis activities, including the conduct of ITCs, and the conceptualisation, implementation, and validation of cost-effectiveness and budget impact models for pharmaceutical, medical device, and policy interventions.

His work in a range of disease areas, including oncology, cardio-renal diseases, rare diseases, inflammatory disorders, and infectious diseases, has informed reimbursement submissions to HTA agencies globally and peer-reviewed publications.

  • Decision modelling
  • Excel
  • VBA
  • R
  • Shiny
  • HTA
  • ITC
  • Diagnostics
  • Medical devices
  • Oncology
  • Cardio-renal
  • Rare diseases
  • Inflammatory disorders
  • Infectious diseases

Services

What we deliver

Projects are bespoke. Use the tabs to see what each service looks like in practice.

Health Economic Modelling

End-to-end modelling, from scoping and conceptualisation through development, QC, validation, analysis, and reporting.

  • Model conceptualisation
  • Model development in Excel, VBA, R, and R Shiny
  • Model adaptation
  • Model QC and validation (conceptual and technical)

Data Analysis

Bespoke, payer-facing analyses using clinical trial data and real-world evidence, with rigorous data management and methodological integrity.

  • Evidence synthesis and ITCs
  • Model parameterisation
  • Survival analysis
  • Patient-reported outcomes analysis
data_analysis.R
## Parameter distributions
cost    <- rgamma(n = 10000, shape = 3.5, scale = 900)
utility <- rbeta(n = 10000, shape1 = 2.2, shape2 = 7.5)
effect  <- rnorm(n = 10000, mean = 0.52, sd = 0.12)
            

HTA Strategy & Technical Advice

Strategic and methodological support for HTA submissions and value demonstration across major frameworks.

  • Evidence and model strategy for HTA submissions
  • Value framework alignment (NICE, CDA, ICER, etc.)
  • Early economic modelling and scenario planning
  • Technical advice on methods, assumptions, and uncertainty

Communication

Translating complex technical work into clear narratives for diverse audiences, including payers, clinicians, and internal leadership alike.

  • Modelling-specific value communication packs
  • Manuscript development and submission
  • Conference proceedings
  • Bespoke training and development
Value Story Slide deck Manuscript

Publications

Peer-reviewed evidence

Search and filter our peer-reviewed journal publications. All titles link to PubMed.

41 publications

Contact

Start a conversation

If you are interested in collaborating with us, exploring our services, or learning more about our company, please fill out the contact form below and we will be in touch.

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Where to find us

Horizon Health Economics is based in Yorkshire and Cardiff, working with clients across the globe.

  • Yorkshire · Cardiff · United Kingdom
  • LinkedIn